The dominating floral species are Dipterocarpus macrocarpus, Terminalia myriocarpa, Shorea assamica, Abies delavayi, Pinus merkusii
Major fauna of the Reserve includes four big cats viz. Panthera tigris, Panthera pardus, Neofelis nebulosa and Panthera uncia range in Namdapha. Hylobates hoolock, Catopuma temminckii, Pardofelis marmorata, Budorcas taxicolor, Ailurus fulgens, Biswamoyopterus biswasi, Asarcornis scutulata are indicative of the unique faunal diversity of Namdapha.